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Purpose of the guideline：
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As a chronic obstructive pulmonary disease, pneumoconiosis poses a serious threat to public health. According to a survey on pneumoconiosis in China, the quality of life of patients is seriously declining, mainly due to an increase in concurrent lung infections. Therefore, this article explores the association between pneumoconiosis and pulmonary infection from multiple perspectives, as well as the expert consensus on diagnosis, treatment, and management plans. This article provides an overview of the clinical characteristics of pneumoconiosis and pulmonary infection, as well as the inherent relationship between the two. Pulmonary tissue lesions in patients with pneumoconiosis increase their susceptibility to infection, especially bacterial, viral, and fungal infections that may lead to acute onset and further deterioration of the condition. Subsequently, the paper elaborated on the diagnostic process of pneumoconiosis combined with pulmonary infection, identifying its key steps and standards, including commonly used imaging, microbiological examination, and biomarker detection. And based on the characteristics of pathogen type, severity of infection, etc., appropriate selection and use of antibiotics have been clarified. Effective treatment of diseases cannot be achieved without individualized case management. In this study, we elaborated on individualized treatment plans based on the activity, severity, and comorbidities of pneumoconiosis and infection, while emphasizing the importance of improving lifestyle habits, nutritional support, early rehabilitation, and psychological support. To avoid pulmonary infection in patients with pneumoconiosis, this article also provides prospects for prevention and control measures, including regular investment in dust prevention equipment and process technology improvement, reducing lung damage caused by dust filaments, and improving immunity to reduce infection rates. In addition, the paper also deepens the future research prospects and prospects. We point out that important progress is being made in the precise diagnosis, treatment, and effective management of pneumoconiosis combined with pulmonary infection. In the future, targeted therapy will be carried out based on the research results of genome, transcriptome, proteome, and metabolome to improve the prognosis and quality of life of pneumoconiosis patients.
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